ILC CS-cfDNA_2025
Price
100,00 €
Variations

Description

Each participating lab will receive two vials of highly characterized wild-type mono-nucleosomal cfDNA, enabling assessment of DNA concentration and size distribution using your routine workflows — all under real-world lab conditions.

Scheme Acronym: CS-cfDNA_2025 (Concentration and Size of cellfree DNA 2025)

Minimum required number of participants: 25

Timeline: Sample shipment is planned for late Summer/Fall 2025 (if minimum number of participants is reached)

Measurands

  1. cfDNA Concentration – Directly measured from the provided buffer
  2. cfDNA Fragment Size Profile – Evaluated to confirm integrity and distribution

Homogeneity & Stability

According to ISO 13528:2022-08

Source

HMEC-1 cells

Formulation and storage

Store at 2 - 8 °C

key_specifications
VAF0%
Cell lineHMEC-1
Concentration20 ng/µL
Product size25 µL
FormulationIn buffer - Tris-EDTA (10 mM Tris, 1 mM EDTA), pH 8.0
Transport temperature2-8 °C
Storage temperature2-8 °C
Quality control
  • Fragmentation size: Bioanalyzer-High Sensitivity DNA Kit Agilent
  • Determination of DNA concentration: Qubit 4, HS DNA assay
Application
  • Mixing with mutant DNA to create different AFs
  • Use as internal control sample for Quality control (DNA size and quantity)
  • Use as internal control sample for evaluating cfDNA extraction efficiency
Right block content

Product category
EQA

Summary

General description

 

The Interlaboratory Comparison (ILC) CS-cfDNA_2025 designed specifically for laboratories working in molecular pathology, liquid biopsy, and related fields. This ILC offers a unique opportunity to evaluate the performance of your methods for quantifying and size-profiling cfDNA and ctDNA prior to dPCR and NGS.

 

Take advantage of this ILC as an External Quality Assessment (EQA) tool to build confidence in your techniques and demonstrate the robustness of your cfDNA analysis methods.

 

Scheduled time of the ILC: late Summer/Fall 2025