Description

Each participating lab will receive two vials of highly characterized wild-type mono-nucleosomal cfDNA, enabling assessment of DNA concentration and size distribution using your routine workflows — all under real-world lab conditions.

Scheme Acronym: CS-cfDNA_2025 (Concentration and Size of cellfree DNA 2025)

Minimum required number of participants: 25

Timeline: Sample shipment is planned for late Summer/Fall 2025 (if minimum number of participants is reached)

Measurands

1. cfDNA Concentration – Directly measured from the provided buffer
2. cfDNA Fragment Size Profile – Evaluated to confirm integrity and distribution

Homogeneity & Stability

According to ISO 13528:2022-08

Source

HMEC-1 cells

Formulation and storage

Store at 2 - 8 °C